论文部分内容阅读
目的 :了解静脉毒瘾者乙型肝炎病毒 (HBV)、丙型肝炎病毒 (HCV)及庚型肝炎病毒 (HGV)的感染状况。方法 :对广东省江门市 12 0例静脉毒瘾者血浆HBV ,HCV和HGV的标记物进行检测 ,采用ELISA法检测HBsAg,HBeAg ,抗HBcAb ,抗HBeAb ,抗HBsAb ,抗HCV抗体 ;逆转录聚合酶链反应 (RT PCR)检测HGVRNA。结果 :12 0例静脉毒瘾者中HBsAg阳性 13例 (10 83% ) ,抗HBsAb阳性 41例 (34 17% ) ,单项抗HBcAb阳性 7例 (5 83% ) ,抗HCV抗体阳性 89例 (74 17% ) ,HGVRNA阳性 2 8例 (2 3 33% )。 13例HBsAg阳性中 9例抗HCV阳性 ,3例HGVRNA阳性 ;7例单项抗HBcAb阳性中 5例抗HCV抗体阳性 ,2例HGVRNA阳性 ;2 8例HGVRNA阳性中 2 0例抗HCV抗体阳性 ;2例HBsAg、抗HCV抗体、HGVRNA同时阳性。结论 :静脉毒瘾者是HCV和HGV的高感染人群 ;HBV ,HCV和HGV三种病毒的感染之间在静脉毒瘾者中无相关性
Objective: To understand the infection status of Hepatitis B virus (HBV), Hepatitis C virus (HCV) and Hepatitis G virus (HGV) in intravenous drug addicts. Methods: The plasma samples of HBV, HCV and HGV from 120 intravenous drug addicts in Jiangmen City, Guangdong Province were detected by ELISA. HBsAg, HBeAg, anti-HBcAb, anti-HBeAb, anti-HBsAb and anti-HCV antibody were detected by ELISA. Enzyme-linked reaction (RT PCR) detection of HGVRNA. Results: Of the 120 intravenous drug addicts, 13 (10 83%) were HBsAg positive, 41 (34 17%) were anti-HBsAb positive, 7 were anti-HBcAb positive 74 17%), HGV RNA positive in 28 cases (2333%). Among the 13 HBsAg positive cases, 9 were anti-HCV positive and 3 were HGV RNA positive. Among the 7 anti-HBcAb positive samples, 5 were anti-HCV antibodies and 2 were HGV RNA positive ones; 20 of 28 HGV RNA positive samples were positive for anti-HCV antibodies; 2 Cases of HBsAg, anti-HCV antibodies, HGVRNA positive at the same time. CONCLUSIONS: Intravenous drug addicts are highly infected with HCV and HGV; there is no association between the infection of HBV, HCV and HGV among intravenous drug users