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目的通过对2例城市人禽流感病例的流行病学调查、分析,探讨无直接病死禽暴露情况下的可能感染来源,为进一步防控禽流感提供科学依据。方法采用现场流行病学、血清学调查的方法;荧光定量PCR、ELISA、RT-PCR和应急监测等方法进行调查、诊断。结果2例感染高致病性禽流感病毒(H5N1)确诊病例未发现有明确病死禽接触史,但发病前到过甚至多次到过农贸市场;密切接触者中没有发生不明原因肺炎病例,未发现人—人传播证据。结论2例人感染高致病性禽流感病例均属城市型感染个案,非人传人病例,感染来源可能与农贸市场环境有关。
Objective To investigate the epidemic situation of human bird flu in two urban areas and to explore possible sources of infection in the case of bird death without direct death and provide a scientific basis for further prevention and control of bird flu. Methods The methods of field epidemiology and serological investigation were used to investigate and diagnose the disease by using fluorescence quantitative PCR, ELISA, RT-PCR and emergency monitoring. Results No confirmed cases of H5N1 infection were detected in the 2 confirmed H5N1 cases. However, they had visited the farmer’s market before or even before the onset of illness. There were no unexplained pneumonia cases in close contacts or cases of unexplained pneumonia Discover people - people spread evidence. Conclusions The two cases of human HPAI are urban infection cases and non-human cases. The source of infection may be related to the market environment of farmers’ markets.