论文部分内容阅读
目的:探讨小儿隐性球菌性脑膜炎临床特点、诊断及治疗。方法:对10例隐性球菌性脑膜炎患儿的临床资料进行回顾性分析。结果:小儿隐性球菌性脑膜炎临床症状、脑脊液特点均不典型,误诊率高,以头痛、发热、脑膜刺激征最为常见。建议对可疑病例要反复多次腰穿进行墨汁涂片或培养查找隐性球菌。两性霉素B加5-氟胞嘧啶联合治疗及两性霉素B鞘注效果明显。结论:隐球菌性脑膜炎为一种难治性疾病,应早期诊断早期治疗,抗真菌疗程要长。
Objective: To investigate the clinical features, diagnosis and treatment of children with occult meningitis. Methods: The clinical data of 10 children with occlusive cocci meningitis were analyzed retrospectively. Results: The clinical manifestations of cryptococcal meningitis in children, cerebrospinal fluid characteristics are not typical, high misdiagnosis, headache, fever, meningeal irritation is the most common. It is recommended to repeatedly suspicious cases of lumbar puncture to smear or culture to find out recessive bacteria. Amphotericin B combined with 5 - fluorocytosine treatment and amphotericin B sheath injection effect is obvious. Conclusion: Cryptococcal meningitis is a refractory disease, early diagnosis and treatment should be early, antifungal therapy longer.