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目的比较海捷压和苯磺酸氨氯地平在治疗原发性高血压血压达标的情况下对肾功能的影响。方法选择2008年610月门诊患者中原发性高血压患者50例,分别给于海捷压和苯磺酸氨氯地平降压治疗使血压达标,1年后对血清内生肌酐清除率进行测算,并进行统计学分析。结果海捷亚组治疗前后内生肌酐清除率改变有统计学意义(P<0.05),苯磺酸氨氯地平组差异无统计学意义(P>0.05)。结论原发性高血压无明显靶器官损害患者,使用苯磺酸氨氯地平和海捷亚使血压达标情况下,海捷亚对肾脏功能的保护作用要优于苯磺酸氨氯地平。
Objective To compare the effects of HITT and amlodipine besylate on renal function in the treatment of essential hypertension blood pressure. Methods Fifty outpatients with essential hypertension were enrolled in this study. They were given Hyperthermia and amlodipine besylate for blood pressure control to achieve the standard of blood pressure. The endogenous creatinine clearance rate was calculated one year later. And statistical analysis. Results Before and after treatment, the rate of endogenous creatinine clearance in Hyperthermia group was statistically significant (P <0.05). There was no significant difference in the amlodipine besylate group (P> 0.05). Conclusion In patients with essential hypertension without obvious target organ damage, the use of Amlodipine besylate and Hetai Ya blood pressure to achieve the standard case, Hytera Ya on renal function better than amlodipine besylate.