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疟原虫是否导致肝脏病变还存在着不同的观点。为了证实有黄疸症状恶性疟病人的肝脏功能及损伤变化以及与并发症的关系,作者对1991年5月至11月间由泰国王玛希杜尔大学热带病医院收治的390例经镜检确诊的急性恶性疟病人(其中124例有黄疸症状,血清总胆红素≥3mg/dl),治疗前后的血清总胆红素、直接胆红素、间接胆红素、天门冬氨酸转氨酶(AST)、丙氨酸转氨酶(ALT)、碱性磷酸酶及白蛋白等进行了测定。有并发症者系指至少伴有下述一种并发症:脑型疟、急性肾衰竭、肺水肿、休克或高原虫血症。
Plasmodium lead to liver disease there are still different views. In order to confirm the changes of liver function and injury in patients with jaundice and symptoms of malaria, and the relationship with complications, the authors analyzed the clinical data of 390 cases of acutely diagnosed acute polyposis admitted to the Tropical Hospital of Maheduo University in Thailand from May to November in 1991. Malaria patients (124 cases had jaundice, serum total bilirubin ≥3mg / dl), serum total bilirubin, direct bilirubin, indirect bilirubin, aspartate aminotransferase (AST) Alanine aminotransferase (ALT), alkaline phosphatase and albumin were measured. Complications are those with at least one of the following complications: cerebral malaria, acute renal failure, pulmonary edema, shock or altitude parasitemia.