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18例常规治疗无效的顽固性心衰(缺血性心脏病9例,原发性心肌病9例)静滴硝普钠,开始15微克/分,每隔3～5分钟增量,至肺动脉模压降至正常或不再继续下降为止,且收缩压不低于100毫米汞柱,最后静滴量为25～120微克/分(平均40微克/分)。13例静滴1～2小时,5例维持24～72小时。结果:静滴时14例呼吸改善,端坐呼吸减轻。治疗前症状严重者临床改善最明显。有出汗的6例出汗停止,有频发室性早搏者其早搏减少甚或消失。左心室充盈压(肺动脉楔压或左室舒张末期压力)从平均32.2降
18 patients with refractory refractory heart failure (ischemic heart disease in 9 cases, 9 cases of primary cardiomyopathy) intravenous infusion of sodium nitroprusside, the beginning of 15 micrograms / minute, every 3 to 5 minutes increase to the pulmonary artery Drops to normal or no longer continue to drop, and systolic blood pressure not less than 100 mm Hg, the final intravenous infusion of 25 to 120 micrograms / min (average of 40 micrograms / min). 13 cases of intravenous infusion of 1 to 2 hours, 5 cases maintained for 24 to 72 hours. Results: 14 cases of intravenous infusion to improve breathing, reduce sitting breathing. Pre-treatment symptoms of severe clinical improvement is most obvious. 6 cases of sweating to stop sweating, frequent premature ventricular contractions reduce or even disappear. Left ventricular filling pressure (pulmonary artery wedge pressure or left ventricular end-diastolic pressure) decreased from an average of 32.2