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本文报道了102例重症肝炎并发多系统脏器衰竭(MSOF)。重症肝炎并发MSOF的发生率为102/136(75％),病死率为82.3％。肝炎病毒不仅损害肝脏而且可直接或间接损害中枢神经系统、凝血系统以及心、肺、肾等器官。重症肝炎是导致发生MSOF的重要因素之一。本文对不同类型重症肝炎并发MSOF的各系统脏器衰竭出现的频度、顺序、脏器衰竭数目与预后的关系等临床特点做了分析,并对重症肝炎并发MSOF的机制做了阐述。
This article reports 102 cases of severe hepatitis complicated by multiple system organ failure (MSOF). The incidence of severe hepatitis with MSOF was 102/136 (75%) and the case fatality rate was 82.3%. Hepatitis virus not only damages the liver, but also directly or indirectly damages the central nervous system, coagulation system, and heart, lung, kidney and other organs. Severe hepatitis is one of the important factors leading to the occurrence of MSOF. This article analyzes the clinical features of the frequency, sequence, the relationship between the number of organ failure and the prognosis of various types of severe hepatitis complicated with MSOF, and elaborates the mechanism of MSOF complicated with severe hepatitis.