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用丹参水溶性提取物,天然正品冬虫夏草对CAH、肝炎后肝硬化进行临床治疗疗效观察,疗程6个月,设秋水仙碱为对照。结果提示:丹参水溶性提取物及天然正品虫草能有效地治疗CAH及肝炎(乙肝)后肝硬化,其总有效率达83％,与秋水仙碱62％相比,有显著差异(P0.05);能显著降低MAO活性,促使P-Ⅲ-P、S-IR-β-PH的下降,说明其能有效地抑制慢性肝病时肝内胶原的合成,阻止慢性肝病的活动,达到抗肝纤维化治疗的目的,且临床运用无明显不良反应。
The water-soluble extract of Salvia miltiorrhiza and natural authentic Cordyceps sinensis were used to observe the curative effect of CAH and post-hepatitis cirrhosis. The treatment period was 6 months. Colchicine was used as the control. The results suggest that the water-soluble extract of Salvia miltiorrhiza and natural Cordyceps militaris can effectively treat CAH and hepatitis (hepatitis B) after liver cirrhosis, the total effective rate is 83%, and there is a significant difference compared with colchicine 62% (P0.05); could significantly reduce MAO activity and promote the decline of P-III-P and S-IR-β-PH. It can effectively inhibit the synthesis of liver collagen in chronic liver disease, prevent the activity of chronic liver disease, achieve the purpose of anti-hepatic fibrosis treatment, and there is no obvious adverse reaction in clinical application.