糖尿病周围神经病变(Diabetic peripheral neuropathy,DPN)是糖尿病最常见的慢性并发症之一,可表现为感觉、运动和自主神经损害症状,严重影响患者的生活质量甚至生命。其发病机制比较复杂,主要有高血糖、氧化应激、微血管病变、代谢异常、神经生长因子缺乏以及自身免疫等多种致病因素。现就近年来中西医药物治疗DPN概况综述如下。 Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. It can show the symptoms of sensory, motor and autonomic nerve damage, and seriously affect the quality of life and even life of patients. The pathogenesis is more complicated, mainly including hyperglycemia, oxidative stress, microangiopathy, metabolic abnormalities, lack of nerve growth factor and autoimmune and other pathogenic factors. In recent years, TCM and Western medicine treatment DPN overview is summarized below.