论文部分内容阅读
目的 探讨乙肝病毒标记(HBVM)向胃腔释放的可能。方法 用ELISA法检测246例胃病患者胃液的HBVM。结果 慢性浅表性胃炎(CSG)、CSG合并十二指肠球部溃疡(DUA)、CSG合并慢性萎缩性胃炎(CAG)、CSG+DUA/CAG和胃癌(Ca)之乙肝病毒表面抗原(HBsAg)检出率分别为5.9％、10.5％、14.8％、19.0％和37.9％;乙肝病毒核心抗体(抗-HBc)分别为52.9％、47.3％、31.1％、33.3％和84.5％。除CSG+DUA/CAG外,胃癌HBsAg与其他各组比较有非常显著性差异(P<0.01);除CSG外,胃癌的抗-HBc与其他各组比较也有非常显著性差异。246例中未检出抗-HBs、HBeAg、抗-HBe和抗-HCV阳性者。结论 提示HBV在感染肝细胞合成过剩时,不仅游离于血液和其它体液,也向胃腔释放——腔释放。
Objective To investigate the possible release of hepatitis B virus (HBVM) into gastric cavity. Methods HBVM of gastric juice in 246 gastric patients was detected by ELISA. Results Hepatitis B virus surface antigen (HBsAg) in chronic superficial gastritis (CSG), CSG combined with duodenal ulcer (DUA), CSG with chronic atrophic gastritis (CAG), CSG + DUA / CAG and gastric cancer ) Were 5.9%, 10.5%, 14.8%, 19.0% and 37.9% respectively. The core antibody against hepatitis B virus (anti-HBc) was 52.9%, 47.3%, 31.1%, 33.3% and 84.5% respectively. Except for CSG + DUA / CAG, HBsAg in gastric cancer was significantly different from other groups (P <0.01). Anti-HBc in gastric cancer was significantly different from other groups except CSG + DUA / CAG. No anti-HBs, HBeAg, anti-HBe and anti-HCV positive were detected in 246 cases. The conclusion suggests that HBV is not only free from blood and other bodily fluids, but also releases to the gastric cavity when the excessive synthesis of hepatocytes is infected.