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从豆科植物传统中药补骨脂(Psoraleacorylifolia L)的种子中,前人曾分出酚、二氢黄酮、香豆精及查耳酮等类化合物。为了筛选,我们仿文献合成了其中所含黄酮及查耳酮成分:补骨脂素(bavachin,1),异补骨脂素(isobavachin,2),补骨脂酮(bavachalcone,3)和异补骨脂酮(isobavachalcone,4)。此外还合成了四个色满衍化物,用甲酸处理2得5,间苯二酚在甲酸、甲酸钠存在下和异戊二烯反应得6。3-(3-甲基-丁烯-2)2,4-
From the seeds of the traditional Chinese herbal medicine Psoraleacorylifolia L., legumes, phenols, dihydroflavonoids, coumarins, and chalcone were identified. In order to screen, we synthesized the contents of flavonoids and chalcone contained in them: bavachin (1), isopavarin (2), bavachalcone (3) and iso Psoralen (isobavachalcone, 4). In addition, four chroman-rich derivatives were also synthesized. Formic acid was used to treat 2 to 5, and resorcinol reacted with isoprene in the presence of formic acid and sodium formate to give 6. 3-(3-methyl-butene-2). 2,4-