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作者测定10例前列腺增生症(BPH)病人血浆睾酮(T),雌二醇(E_2)及E_2/T比值,并对照10例非前列腺增生症(NPH)男性老年者。结果显示:1、性激素各项指标值与年龄不成正比;2、性激素水平与前列腺增大程度不相关;3、BPH组与NPH组血浆T无显著差异(P>0.05),E_2及E_2/T前者比后者显著提高(P<0.01)。提示雌雄激素比例失衡可能是BPH的发病因素。
The authors measured plasma testosterone (T), estradiol (E 2) and E 2 / T ratio in 10 patients with benign prostatic hyperplasia (BPH) and compared 10 elderly non-benign prostatic hyperplasia (NPH) men. The results showed that: 1, sex hormone values ?? are not proportional to age; 2, sex hormone levels and prostate enlargement is not related; 3, BPH group and NPH plasma T had no significant difference (P> 0.05), E 2 and E 2 / T The former was significantly higher than the latter (P <0.01). Suggesting that the imbalance of estrogen androgen may be the pathogenesis of BPH.