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本文旨在证明支气管肺泡灌洗液(BALF)中的石棉小体(AB)是否可用于估价肺AB 浓度和BAL 是否可作为AB 的体内取样的方法。受试者100例(男93,女7)平均年龄61.4±8.2岁。其中95例(84例肺癌)曾进行1侧肺切除术,余5例经胸腔作肺活检。22例肯定有石棉接触史,15例可能有石棉接触史,63例不明。100份BALF 样品中的68份和100份肺样品中的9份检测了AB 的浓度。结果表明BALF 中AB 的浓度为0～3500AB/ml,肺组织中0～1663 000AB /g 肺。发现16/33(48.5%)的白领工人BALF 中有AB,平均(对数)值为0.14AB/ml,4/33(12%)的BALF样品中的含量高于1 AB/ml,没有1个样品的含量超
This article aims to demonstrate whether asbestosis (AB) in bronchoalveolar lavage fluid (BALF) can be used to evaluate lung AB concentration and whether BAL can be used as an in vivo sampling method for AB. The average age of the 100 subjects (male 93, female 7) was 61.4±8.2 years. Ninety-five patients (84 lung cancers) underwent one-sided lung resection, and the remaining five patients underwent transthoracic lung biopsy. There were certainly asbestos exposures in 22 cases, asbestos exposure history in 15 cases, and unknown in 63 cases. The concentration of AB was detected in 68 of 100 BALF samples and 9 of 100 lung samples. The results showed that the concentration of AB in BALF ranged from 0 to 3500 AB/ml and that of lung from 0 to 1663 000 AB/g lung. 16/33 (48.5%) white-collar workers were found to have AB in the BALF with an average (log) value of 0.14 AB/ml, and 4/33 (12%) of the BALF samples were higher than 1 AB/ml, with no 1 Super sample content