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目的探讨糖尿病合并焦虑抑郁状况及黛力新联合胰岛素泵治疗糖尿病焦虑抑郁的疗效及安全性。方法收集住院2型糖尿病患者,均为注射胰岛素血糖控制差者,采用Zung的焦虑抑郁自评量表进行问卷调查,SDS,SAS标准分≥50的患者60例入组,随机分两组,均采用胰岛素泵治疗两周,两周后改为诺和灵30R皮下注射。治疗组同时口服黛力新一片,晨服,观察8周。比较SDS,SAS值及黛力新药物不良反应。结果两组血糖均较治疗前明显下降,两组SDS,SAS值均较治疗前下降,治疗组下降得更明显(P<0.05)。结论糖尿病血糖控制欠佳容易合并焦虑抑郁,黛力新联合胰岛素泵治疗血糖控制得更好,同时有效改善焦虑抑郁情绪障碍。
Objective To investigate the efficacy and safety of diabetes mellitus with anxiety and depression and Deanxpress combined with insulin pump in the treatment of diabetic anxiety and depression. Methods Inpatients with type 2 diabetes mellitus were enrolled in this study. All patients with poor control of insulin blood glucose were surveyed by using Zung’s anxiety and depression self-rating questionnaire. Sixty patients with SDS and SAS ≥ 50 were randomly assigned into two groups, Insulin pump treatment for two weeks, two weeks later to Norvir 30R subcutaneous injection. The treatment group also oral Deanxu a new morning service, observed for 8 weeks. SDS, SAS value and Deanxit drug adverse reactions were compared. Results The blood glucose of the two groups decreased significantly compared with that before treatment. The SDS and SAS values decreased in both groups before treatment and decreased more significantly in the treatment group (P <0.05). Conclusion Poor glycemic control in diabetic patients is easily combined with anxiety and depression. Dextrins combined with insulin pump can better control blood sugar and improve anxiety and depression emotion.