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氟伐普坦(frovatriptan)是5-HT1B/1D受体强激动剂和5-HT7受体中等激动剂。氟伐普坦对离体人基底动脉和冠状动脉有强力的收缩作用,其强度为舒马普坦(rumatriptan)的8倍。5项随机、双盲、安慰剂对照临床试验(3128例)结果表明,用氟伐普坦(2.5mg口服)者偏头痛复发率(7%～25%)低于用
Frovatriptan is a 5-HT1B / 1D receptor agonist and a 5-HT7 receptor moderate agonist. Fluvastatin exerts a potent contractile effect on isolated human basilar and coronary arteries with an intensity eight times that of rumatriptan. Five randomized, double-blind, placebo-controlled clinical trials (3128 patients) showed that the recurrence rate (7% -25%) of migraine with vaspamtagine (2.5 mg orally)