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目的观察丁苯酞氯化钠注射液治疗基底动脉尖综合征(TOBS)的临床疗效。方法将60例TOBS患者随机分为对照组和观察组,对照组按照缺血性脑血管病给予常规治疗,观察组在对照组基础上加用丁苯酞氯化钠注射液静脉滴注,疗程14d。采用NIHSS评分及BI评分评价治疗前和治疗后第14天两组患者的神经功能与日常生活能力。结果与治疗前比较,两组治疗后的NIHSS评分降低,BI评分升高,差异有统计学意义(P<0.05),与对照组比较,观察组治疗后第14天的NIHSS评分明显降低,BI评分明显升高,差异有统计学意义(P<0.05)。结论丁苯酞治疗TOBS具有良好的临床疗效。
Objective To observe the clinical efficacy of butylphthalide and sodium chloride injection in the treatment of basilar artery syndrome (TOBS). Methods Sixty TOBS patients were randomly divided into control group and observation group. The control group was given routine treatment according to ischemic cerebrovascular disease. The observation group was given intravenous infusion of sodium butylphthalide and sodium chloride injection on the basis of the control group. 14d. The NIHSS score and BI score were used to evaluate the neurological function and daily living ability of the two groups before treatment and 14 days after treatment. Results Compared with those before treatment, NIHSS score decreased and BI score increased after treatment in both groups (P <0.05). Compared with the control group, the NIHSS score of the observation group decreased significantly on the 14th day after treatment The score was significantly higher, the difference was statistically significant (P <0.05). Conclusion Butylphthalide treatment of TOBS has a good clinical effect.