近年来,关于白细胞介素2(IL-2)和可溶性白细胞介素2受体(sIL-2r)的研究日益受到重视,有文献报道,用短期大剂量肾上腺糖皮脂激素治疗5例MDS患儿,其中3例CMML患儿在接受治疗后血清中IL-2活性有明显提高。本文应用短期大剂量甲基强的松龙,结合常规化疗,对23例CMML患儿进行治疗,并对其血清中IL-2及sIL-2r水平进行了测定,现报道如下。 In recent years, the research on interleukin 2 (IL-2) and soluble interleukin 2 receptor (sIL-2r) has been paid more and more attention. It has been reported in the literature that 5 cases of MDS with short-term high-dose glucocorticoid treatment , Of which 3 cases of children with CMML after treatment serum IL-2 activity was significantly improved. In this paper, the application of short-term high-dose methylprednisolone, combined with conventional chemotherapy, 23 cases of CMML children were treated, and serum IL-2 and sIL-2r levels were measured, are reported below.