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目的 :探讨鼻腔、咽部非霍奇金氏淋巴瘤 ( NHL)的临床特征、诊断要点及误诊原因。方法 :对1 986年～ 1 996年住院的 2 4例鼻腔、咽部非霍奇金氏淋巴瘤的患者作一回顾性分析。结果 :2 4例临床表现差异较大 ,缺乏特征性的表现。首次诊断 NHL6例 ,其余 1 8例初诊时诊断 :慢性鼻炎 8例 ,恶性肉芽肿3例 ,鼻息肉 2例 ,鼻中隔粘膜肥厚 2例 ,扁桃体炎 2例 ,慢性咽炎 1例。 2 4例均经病理切片及免疫组化确诊。结论 :鼻腔、咽部非霍奇金氏淋巴瘤临床表现复杂 ,缺乏特征性 ,早期易误诊。提高临床医师对本病的认识 ,反复活检及免疫组化等方法有利于本病的确诊。
Objective : To investigate the clinical features, diagnosis and misdiagnosis reasons of nasal and pharyngeal non-Hodgkin’s lymphoma (NHL). Methods: A retrospective analysis of 24 patients with nasal and pharyngeal non-Hodgkin’s lymphoma hospitalized from 1896 to 1996 was performed. Results: The clinical manifestations of 24 cases were quite different and there was no characteristic performance. The first diagnosis of NHL6 cases, the remaining 18 cases diagnosed at the time of initial diagnosis: 8 cases of chronic rhinitis, malignant granuloma in 3 cases, 2 cases of nasal polyps, nasal septum mucosal hypertrophy in 2 cases, tonsillitis in 2 cases, 1 case of chronic pharyngitis. All 24 cases were confirmed by pathological section and immunohistochemistry. Conclusion : The clinical manifestations of nasal and pharyngeal non-Hodgkin’s lymphomas are complex and lack of characteristics. They are often misdiagnosed in the early stage. Raising the clinician’s awareness of this disease, repeated biopsy, and immunohistochemistry are beneficial to the diagnosis of the disease.