论文部分内容阅读
用免疫组织化学 SP法对无水乙醇栓塞后肾癌手术标本 36例及同期单纯手术切除标本1 0例中微血管数目、碱性成纤维生长因子 (b FGF)和其受体 (FGF- R)的表达进行检测 ,并进行比较。结果显示术前栓塞组的微血管数目低于手术对照组 ,且差异有显著性 (P <0 .0 0 1 ) ;b FGF和FGF- R的表达具有一致性 ,术前栓塞组 b FGF和 FGF- R阳性率为 55.6% ,手术对照组 b FGF和FGF- R阳性率为 60 % ,两组相比无显著性差异 (P >0 .0 5)。提示无水乙醇栓塞能够降低肾肿瘤微血管数目 ,并减少肿瘤血行转移的可能性
Immunohistochemistry (SP) was used to determine the number of microvessel, basic fibroblast growth factor (bFGF) and its receptor (FGF-R) in 36 cases of renal cell carcinoma and 10 cases of simple surgical resection in the same period. The expression was detected and compared. The results showed that the number of microvessels in preoperative embolization group was lower than that in surgical control group, and the difference was significant (P0.01); the expression of b FGF and FGF-R was consistent. Preoperative embolization group b FGF and FGF - The positive rate of R was 55.6%. The positive rate of b FGF and FGF-R in the control group was 60%. There was no significant difference between the two groups (P> 0.05). Prompted absolute ethanol embolization can reduce the number of renal tumor microvessels, and reduce the possibility of tumor hematogenous metastasis