目的对比分析静脉给药咪达唑仑与传统联合方案治疗反复性小儿惊厥的疗效及安全性。方法选择88例反复性小儿惊厥患者为研究对象,行随机数字表法均分,观察组行静脉给药咪达唑仑治疗,对照组行传统联合方案,交替使用地西泮、苯巴比妥。观察两组疗效及不良反应发生率。结果观察组总有效率为93.2%,对照组为77.2%,观察组总有效率显著性高于对照组(χ2=4.223,P=0.035);观察组心率及血压未发生显著变化,且未出现明显不良反应,对照组心率和血压均显著降低,且出现6例呼吸抑制。结论静脉给药咪达唑仑治疗反复性小儿惊厥疗效好、安全性高,值得推广。 Objective To compare the efficacy and safety of intravenous midazolam with traditional regimens in the treatment of recurrent pediatric convulsions. Methods Eighty-eight patients with recurrent pediatric convulsions were selected as subjects, equally divided by random number table. Patients in observation group were treated with midazolam intravenously, while those in control group were treated with traditional combination regimen. Diazepam and phenobarbital . The curative effect and incidence of adverse reactions in both groups were observed. Results The total effective rate was 93.2% in the observation group and 77.2% in the control group, and the total effective rate in the observation group was significantly higher than that in the control group (χ2 = 4.223, P = 0.035). There was no significant change in heart rate and blood pressure in the observation group Significant adverse reactions, heart rate and blood pressure in the control group were significantly reduced, and 6 cases of respiratory depression. Conclusion Intravenous midazolam treatment of recurrent pediatric convulsions good effect, high safety, it is worth promoting.