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本文对22例老年高血压与23例血压匹配相当的非老年高血压的肾素水平、细胞内离子、血流动力学指标及对药物的降压反应作对比性分析.结果发现,老年组的心输出量、心指数、快速充盈量、血管顺应性降低较非老年组更为明显,外周阻力及细胞内钙含量显著升高,均有统计学差别.细胞内钙含量的升高可能是血管壁僵硬、顺应性降低的分子学基础.在对硝苯吡啶的降压效应方面,老年组血压下降后血流动力学的改善较非老年组为差
This article 22 cases of elderly hypertension and 23 cases of blood pressure matching non-elderly hypertension renin levels, intracellular ions, hemodynamics and antihypertensive drugs for comparative analysis of the results showed that the elderly group Cardiac output, cardiac index, rapid filling volume, vascular compliance decreased more significantly than non-elderly group, peripheral resistance and intracellular calcium content increased significantly, both statistically significant differences in intracellular calcium levels may be vascular Wall stiffness, decreased compliance of the molecular basis of nifedipine in the antihypertensive effect, the elderly group decreased blood pressure hemodynamic improvement than the non-elderly group was poor