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类胰岛素生长因子(IGFs)又称生长介素,是一组生长激素(GH)依赖性多肽,其主要功能是介导GH的蛋白同化作用和促有丝分裂作用.现就IGFs的结构、受体、结合蛋白及其临床意义综述如下.
Insulin-like growth factor (IGFs), also known as growth hormone, is a group of growth hormone (GH) -dependent polypeptide whose main function is to mediate the protein assimilation and mitogenic effects of GH. The binding proteins and their clinical implications are summarized below.