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甲硝唑(Metronidazolc,灭滴灵,甲硝哒唑)为咪唑衍生物.此药原为抗滴虫特效药,继又发现对阿米巴也有强大作用,而被用于治疗肠内外阿米巴病.近年来,该药的新用途不断被发现,广用于内、儿、皮肤、口腔及外科.特别是外科,目前公认为抗厌氧菌感染的首选药物,疗效颇佳.又因其毒性小,安全性较大,价格相对便宜,深受外科临床医生青睐.但该药在临床应用中也出现一些毒副反应.本文试根据近年来的有关文献资料综述如下,借以引起外科临床医生使用时的注意.
Metronidazole (Metronidazol, metronidazole, metronidazole) is an imidazole derivative of the drug was originally for trichomonad effective drugs, then also found that there is a strong effect on amoeba, and is used to treat enteral amure In recent years, the new use of the drug continue to be found, widely used in the internal, children, skin, oral and surgical, especially surgery, is currently recognized as the preferred drug against anaerobic infections, the effect is quite good.Because of its small toxicity , Safety, relatively cheap, favored by surgical clinicians.But the drug in the clinical application of some toxic and side effects.This paper based on the literature review in recent years are summarized below, in order to cause the surgeon to use Attention.