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目的探讨胃镜与腹腔镜双镜联合及内镜黏膜下挖除术(endoscopic submucosal excavation,ESE)治疗胃肠道间质瘤的效果和安全性。方法经胃(肠)镜、超声内镜及病理学、免疫组化证实的胃肠道间质瘤患者37例,对其中28例患者采用ESE、9例采用胃镜与腹腔镜双镜联合进行瘤体切除。结果 ESE及双镜联合治疗的所有患者均完整切除瘤体,两种方法均无术中及术后迟发性出血、剧烈腹痛等并发症,瘤体位于贲门者,切除后患者贲门功能保持良好,术后随访无复发。结论胃镜与腹腔镜双镜联合技术及ESE是治疗胃肠道间质瘤的微创、安全、有效的新方法。
Objective To investigate the efficacy and safety of endoscopic submucosal excavation (ESE) combined with gastroscopy and laparoscopy in the treatment of gastrointestinal stromal tumors. Methods Thirty-seven patients with gastrointestinal stromal tumors confirmed by gastroscopy, endoscopic ultrasonography, pathology and immunohistochemistry were enrolled in this study. ESE was performed on 28 of them, and 9 patients underwent endoscopy combined with laparoscopy Body excision. Results All patients with ESE and double-mirror combined treatment had complete resection of the tumor. Both of the two methods were free of intraoperative and postoperative delayed hemorrhage, severe abdominal pain and other complications. The tumor was located in the cardia and the cardiac function remained well after resection No recurrence after follow-up. Conclusion Gastroscopy combined with laparoscopy and ESE is a new minimally invasive, safe and effective method for the treatment of gastrointestinal stromal tumors.