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目的:分析慢性阻塞性肺疾病并呼吸衰竭行纳洛酮与无创正压通气效果及预后。方法:资料选取我院2015年8月-2016年8月收治的65例COPD并呼吸衰竭患者予回顾性分析,依据不同治疗方案将其分为对照组与研究组,前者30例单纯予NPPV治疗,后者35例联合纳洛酮治疗,比较两组治疗前后动脉血气相关指标及肺功能情况。结果:两组动脉血气指标均治疗前均改善,但研究组改善幅度优于对照组(P<0.05);研究组肺功能指标高于对照组(P<0.05)。结论:NPPV联合纳洛酮治疗COPD并呼吸衰竭患者可有效改善其血气指标,并提高肺功能,具推广应用价值。
Objective: To analyze the effect and prognosis of naloxone and noninvasive positive pressure ventilation in chronic obstructive pulmonary disease and respiratory failure. Methods: Data of 65 COPD patients with respiratory failure admitted to our hospital from August 2015 to August 2016 were retrospectively analyzed. According to different treatment regimens, they were divided into control group and study group. The former 30 patients were treated with NPPV alone , The latter 35 cases of combined naloxone treatment, arterial blood gas-related indicators and pulmonary function before and after treatment were compared. Results: The arterial blood gas index of both groups improved before treatment, but the improvement rate of the study group was better than that of the control group (P <0.05). The lung function index of the study group was higher than that of the control group (P <0.05). Conclusion: NPPV combined with naloxone in patients with COPD and respiratory failure can effectively improve its blood gas index, and improve lung function, with the promotion and application value.