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[英]／CythiaAW／JImmunol．-1996，156．－1442～1447T辅助细胞表型的发育可能是对特异性病原因子抵抗的应急反应。在鼠实验性leishmaniasis中TH1应答的发展赋以对病原因子的抵抗力，而TH2应答则给以致死性病原因子的传播。IL－12，IL－4分别对天然（naive）T细胞向TH1和TH2亚
[English] / CythiaAW / JImmunol. -1996,156. The development of the -1442-1447T helper cell phenotype may be an emergency response to specific pathogen resistance. The development of TH1 responses in murine experimental leishmaniasis confers resistance to pathogenic agents, whereas TH2 responses give the spread of lethal pathogens. IL-12 and IL-4 sub-differentiate naive T cells into TH1 and TH2, respectively