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目的探讨肥胖因素与男性生殖功能的关联性,为治疗男性不育提供理论依据。方法随机选取男科生殖门诊进行孕前健康查体者,根据BMI指数分为正常体重组(BMI:18.5~23.9 kg/m~2)、超重组(BMI:24~27.9 kg/m~2)和肥胖组(BMI:≥28 kg/m~2)。并检测其精液常规(精液量、精液密度、正常形态率、存活率、前向运动精子、活力a和活力b)和性激素五项(促卵泡生成素FSH、促黄体生成素LH、睾酮T、泌乳素PRL、雌二醇E2),并对检测结果进行统计学分析。结果共调查144例病人,其中正常体重组50例、超重组47例和肥胖组47例。3组精液量和精液密度差异有统计学意义(P<0.05),BMI指数与精液量之间呈负相关(r=-0.427,P<0.05)。与正常组相比,雌二醇是逐渐升高的。促黄体生成素与BMI指数呈相关性。结论肥胖是影响男性生殖功能的一个重要因素。
Objective To explore the association between obesity and male reproductive function and to provide a theoretical basis for the treatment of male infertility. Methods According to the BMI index, we randomly selected male genital clinics for pre-pregnancy physical examination and divided them into normal weight group (BMI: 18.5-23.9 kg / m ~ 2), overweight group (BMI: 24-27.9 kg / Group (BMI: ≥28 kg / m ~ 2). The sperm routine (sperm concentration, sperm density, normal morphology, survival rate, motile sperm motility, vitality a and vitality b) and five sex hormones (follicle stimulating hormone FSH, luteinizing hormone LH, testosterone T, Prolactin PRL, estradiol E2), and the test results were statistically analyzed. Results A total of 144 patients were investigated, of which 50 were in normal weight group, 47 in overweight group and 47 in obesity group. There was a significant difference between semen volume and semen density in the three groups (P <0.05). There was a negative correlation between BMI index and semen volume (r = -0.427, P <0.05). Compared with the normal group, estradiol is gradually increased. Luteinizing hormone was associated with BMI. Conclusion Obesity is an important factor affecting male reproductive function.