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目的总结直肠神经内分泌肿瘤(RNEN)的临床诊断和治疗方法。方法回顾性分析2009年1月至2013年12月期间南京中医药大学附属医院(江苏省中医院)收治的16例RNEN患者的临床资料。结果 16例患者均顺利完成手术,手术时间30~120 min,平均50 min;术中出血量10~80 m L,平均55 m L;均无手术死亡,术中均未见严重并发症发生。术后住院时间10~35 d,平均17 d。手术创面均一期愈合,均顺利出院。术后所有患者均获访,随访时间为2个月~5年,中位随访时间为20个月。随访期间所有患者均未见复发或转移,无死亡病例。结论 RNEN发病隐匿,具有恶性潜能,且常无特异性临床表现,故应加深对该病的认识,及时对就诊患者进行全面检查,做到早发现、早诊断及早治疗,且治疗后应对患者进行严密随访。
Objective To summarize the clinical diagnosis and treatment of rectal neuroendocrine tumors (RNEN). Methods The clinical data of 16 patients with RNEN admitted to the Affiliated Hospital of Nanjing University of Traditional Chinese Medicine (Jiangsu Provincial Hospital) from January 2009 to December 2013 were retrospectively analyzed. Results All the 16 patients completed the operation successfully. The operation time was 30-120 minutes, with an average of 50 minutes. The intraoperative blood loss was 10-80 m L, with an average of 55 m L. No operative death occurred and no serious complications occurred during the operation. Postoperative hospital stay was 10-35 days, with an average of 17 days. All surgical wounds were healed and all were discharged. All patients were visited after surgery. The follow-up time was 2 months to 5 years, and the median follow-up time was 20 months. During the follow-up period, no recurrence or metastasis occurred in all patients and no deaths occurred. Conclusion The RNEN is insidious, has malignant potential, and often has no specific clinical manifestations. Therefore, it is necessary to deepen the understanding of the disease and conduct a comprehensive examination of the patients in a timely manner to achieve early detection, early diagnosis and early treatment, and to treat patients after treatment. Followed closely.