自从20世纪80年代中期吲哒帕胺(inda-pamide)在澳大利亚上市以来,澳大利亚药物不良反应顾问委员会已收到164份使用吲哒帕胺引起低钠血症的报告,这是委员会成立30年来引起低钠血症报告最多的药物。在164份报告中,有68份同时伴有低钾血症。大部分是老年患者,其中88%≥65岁,且妇女 Since indomethacin was introduced in Australia in the mid-1980s, the Australian Adverse Drug Adviser’s Advisory Board has received 164 reports of the use of indapamide to cause hyponatremia, which is the first time in 30 years since its establishment Drugs that cause the most reports of hyponatremia. Of the 164 reports, 68 were accompanied by hypokalemia. Most are elderly patients, of whom 88% ≥65 years and women