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目的探讨儿童交替性偏瘫病因、临床特点、治疗效果。方法回顾性分析3例儿童交替性偏瘫患者的病因、临床表现及疗效。结果本组3例患者起病年龄均小于18个月,反复发作的交替性偏瘫；进行性的智能障碍,其中1例伴有短暂眼球震颤及眼球活动障碍,1例伴有张力障碍性姿势异常；睡眠可缓解无力及锥体外系症状,应用氟桂嗪治疗后,2例患者发作频率及持续时间降低,1例无效。结论本病病因不明,多为散发,临床表现为18月内起病的发作性交替性偏瘫,辅助检查无特征性改变,氟桂利嗪治疗部分有效。
Objective To explore the etiology, clinical features and therapeutic effect of children with alternative hemiplegia. Methods Retrospective analysis of 3 cases of children with alternative hemiplegia etiology, clinical manifestations and efficacy. Results The 3 patients in this study all had less than 18 months onset of recurrent hemiplegia, progressive intellectual disorders including transient nystagmus and ocular motility disorder, and 1 patient with dystonic posture abnormalities ; Sleep can alleviate the weakness and extrapyramidal symptoms, the application of flunarizine treatment, 2 patients seizure frequency and duration decreased, 1 case of ineffective. Conclusion The etiology of this disease is unknown, mostly sporadic. The clinical manifestations are episodic alternating hemiplegia with onset in 18 months. There is no characteristic change in auxiliary examinations. Flunarizine treatment is partly effective.