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目的比较帕金森氏病(PD)与脑梗死引起的血管性帕金森氏综合征(VP)的临床表现,以及抗震颤麻痹药(抗 PD 药)对两种疾病的不同治疗效果。方法对长期门诊随访或住院的27例 PD 患者及10例脑梗死引起的 VP 患者的临床表现及对抗 PD 药物的治疗效果进行比较分析。结果 PD 患者临床上多以震颤或震颤-僵直一少动起病(77.4%);而 VP 患者多以对称性铅管样肌僵直一少动起病(74.4%),静止性震颤少见,可伴有锥体束损害表现、智能障碍和尿失禁;两组比较有显著性差异。抗 PD 药物对 PD 患者有效率为(86.4%).优于 VP 患者的有效率(22.5%),两组比较有显著性差异(P<0.05)。
Objective To compare the clinical manifestations of Parkinson’s disease (VP) caused by Parkinson’s disease (PD) and cerebral infarction with the different therapeutic effects of anti-Parkinsonism (anti-PD) on the two diseases. Methods The clinical manifestations of 27 patients with long-term outpatient follow-up or hospitalized patients with PD and 10 patients with cerebral infarction caused by VP and the efficacy of anti-PD drugs were compared. Results Most patients with PD had tremor or tremor-onset of agility-less onset (77.4%). In patients with VP, the symmetry of lead-like muscle was more or less severe (74.4%), and rest tremor was uncommon. Accompanied by pyramidal tract damage performance, mental retardation and urinary incontinence; two groups were significantly different. The anti-PD drug was effective in PD patients (86.4%), superior to VP patients (22.5%), there was significant difference between the two groups (P <0.05).