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目的 探讨立体定向放射治疗肺肿瘤的近期疗效。方法 立体定向放射治疗２１ 例肺肿瘤。肿瘤体积８～３８８ ｃｍ ３。鳞状细胞癌１０ 例，腺癌７ 例，小细胞癌２ 例，恶性黑素瘤肺转移１ 例，骨肉瘤肺转移１ 例。 Ｓ Ｔ Ａ Ｒ１０００立体定向计划系统制作计划，直线加速器８ Ｍ Ｖ Ｘ 射线实施治疗。 Ｂ Ｅ Ｖ 方向５～８ 个非共面照射野， Ｐ Ｔ Ｖ 一次治疗剂量５～１０ Ｇｙ，总剂量为２５～５０ Ｇｙ。 Ｓ Ｒ Ｔ 疗程为１～２ 周。结果 ６ 周后 Ｃ Ｔ 复查， Ｃ Ｒ 率４８％ ， Ｐ Ｒ 率４３％ ，总有效率９１％ 。结论 Ｓ Ｒ Ｔ 临床应用可提高肿瘤局部的控制率。 Ｓ Ｒ Ｔ治疗剂量与亚临床淋巴引流区的常规放疗剂量应一同计划设计。 Ｓ Ｒ Ｔ 的合理应用尚需进一步的临床研究和随访。
Objective To investigate the short-term efficacy of stereotactic radiotherapy for lung cancer. Methods Stereotactic radiotherapy for 21 lung tumors. The tumor volume is 8-388 cm 3 . There were 10 cases of squamous cell carcinoma, 7 cases of adenocarcinoma, 2 cases of small cell carcinoma, 1 case of malignant melanoma lung metastasis, and 1 case of osteosarcoma lung metastasis. S T A R 1000 Stereotactic planning system production plan, linear accelerator 8 M V X ray treatment. 5 to 8 non-coplanar irradiation fields in B E V direction, P T V treatment dose 5–10 Gy, total dose 25–50 Gy. S R T treatment for 1 to 2 weeks. Results After 6 weeks of CRT review, C R rate was 48%, P R rate was 43%, and total effective rate was 91%. Conclusion Clinical application of S R T can improve the local tumor control rate. The SRT therapeutic dose should be planned together with the conventional radiotherapy dose in the subclinical lymphatic drainage area. The rational application of S R T still requires further clinical studies and follow-up.