奥沙利铂（oxahplatin）是新一代有效治疗晚期结肠直肠癌的钥衍生物。临床前研究表明本品对人和鼠肿瘤细胞均有广泛的抑制作用，且对各种倾铂耐药的肿瘤细胞株无交叉耐药。体内外实验表明本品与5一氟尿啼院联用有协同增效作用。临床资料表明治疗转移性结肠直肠癌时本品单用或与 Oxahplatin is a new generation of key derivatives that are effective in the treatment of advanced colorectal cancer. Preclinical studies have shown that this product has extensive inhibitory effects on human and murine tumor cells, and there is no cross-resistance to various platinum-resistant tumor cell lines. In vitro and in vivo experiments showed that this product has a synergistic effect with 5-fluorouracil brothel. Clinical data show that this product is used alone or with metastatic colorectal cancer