急性高原肺水肿发病机理高原空气含氧量低,低氧是肺水肿的直接致病因素,它能使人体与高原环境间氧的供需平衡失调,引起机体各系统发生复杂的急性代偿适应的病理生理改变,即人体环境统一——病理生理反应。初到高原低氧环境后,机体各系统都先后出现一系列生理代偿过程,如组织机能活力增强,细胞内酶活性及代偿发生变化,使组织细胞在低氧条件下维持正常功能。于是临床上出现一系列症状,即高原反应,就是机体对高原的应激反应。机体如果适应性代偿功能差或不全,必然引起组织细胞功能紊乱和各脏器代偿障碍,临床出现轻重不同、长短各异的高山不适应或失代偿的反应病态,这通称高山病。假使得不到及时治疗,致病因素不能及时解除,机体得不到改善,继续缺氧,就会引起肺血容量增加,肺动脉高压,致使肺泡毛细 The pathogenesis of acute altitude pulmonary edema Plateau air oxygen content is low, hypoxia is a direct risk factor for pulmonary edema, it can make the human body and the plateau environment oxygen supply and demand imbalance between the body caused by a complex system of acute compensatory adaptation Pathophysiological changes, that is, the unity of the human environment - pathophysiological responses. After the plateau began to hypoxia environment, the body system has a series of physiological compensatory process, such as organizational performance increased vitality, intracellular enzyme activity and compensatory changes, so that cells in hypoxia conditions to maintain normal function. So a series of clinical symptoms, that is, altitude sickness, is the body’s stress response to the plateau. If the body compensatory function is poor or incomplete, will inevitably lead to organizational dysfunction of cells and organ compensatory disorders, clinical severity, length of different high mountain unsuitable or decompensated sick, which is commonly known as mountain sickness. If you do not get timely treatment, pathogenic factors can not be promptly lifted, the body can not be improved to continue hypoxia, it will cause increased pulmonary blood volume, pulmonary hypertension, resulting in alveolar capillary