报告先天性精神发育不全67例的皮纹分析结果,经与染色体核型分析对照,发现染色体无异常的患者皮纹类似正常人,而染色体异常者(皆属Down综合征)有明显异常:手指尺箕、手掌小鱼际区及指间区Ⅲ(Ⅰ_3)具真实花纹均多于正常人;atd角度、tPD和通贯手亦明显增大和出现率增高,(足母)趾球部以胫侧弓居多,认为上述异常皮纹组合为染色体畸变所致并可作为本病患者染色体检查筛选和Down综合征的辅助诊断指标之一。 67 cases of congenital mental retardation reported dermatoglyphics results, and chromosome karyotype analysis of control and found no abnormal chromosomes in patients with dermatoglyphosis similar to normal, and chromosomal abnormalities (all Down syndrome) were significantly abnormal: finger At the angle of atd, the tPD and the penetrating hand also increased significantly and the incidence rate increased. The maxillary peduncle and the interdigital region Ⅲ (Ⅰ_3) had more actual patterns than the normal ones. Side of the bow mostly, that the combination of abnormal dermal layer caused by chromosome aberrations and can be used as the patient’s chromosomal screening and Down syndrome syndrome diagnosis of one of the indicators.