论文部分内容阅读
目的观察布地奈德(普米克令舒)雾化吸入佐治小儿毛细支气管炎的临床疗效及安全性。方法选择2012年12月—2014年3月我院收治的毛细支气管炎患儿124例,将其随机分为对照组和治疗组,各62例。对照组患儿采用常规综合对症治疗,治疗组患儿在常规综合对症治疗的基础上雾化吸入普米克令舒,均连续治疗1周。记录两组患儿临床症状消失时间,包括:咳嗽消失时间、喘憋消失时间及肺部啰音消失时间。观察两组患儿治疗效果及治疗期间不良反应情况。结果治疗组患儿咳嗽消失时间为(4.8±3.0)d、喘憋消失时间为(2.1±1.1)d、肺部啰音消失时间为(5.1±2.7)d,均短于对照组的(7.0±2.2)d、(3.3±1.4)d、(8.1±1.1)d(P<0.05)。治疗组患儿总有效率为93.5%,高于对照组的75.8%(P<0.05);治疗组患儿不良反应发生率为4.8%,低于对照组的8.1%(P<0.05)。结论普米克令舒雾化吸入佐治小儿毛细支气管炎具有显著的疗效,能够有效改善患儿临床症状,且操作简易,安全性高,值得临床推广使用。
Objective To observe the clinical efficacy and safety of budesonide (pulmicort) aerosol inhalation for children with bronchiolitis. Methods 124 patients with bronchiolitis admitted to our hospital from December 2012 to March 2014 were randomly divided into control group and treatment group, with 62 cases in each group. The control group of children with conventional comprehensive symptomatic treatment, treatment group children in the conventional comprehensive symptomatic treatment based on inhalation of pulmicort respules, were treated for 1 week. Record the disappearance of clinical symptoms in both groups, including the disappearance of cough, the disappearance of wheezing and the disappearance of pulmonary rales. The therapeutic effects of the two groups were observed and the adverse reactions during treatment were observed. Results The duration of cough disappearance in the treatment group was (4.8 ± 3.0) days, (2.1 ± 1.1) days in asthma disappearance and (5.1 ± 2.7) days in pulmonary rales, which were both shorter than those in control group (7.0 ± 2.2 d, 3.3 ± 1.4 d, 8.1 ± 1.1 d (P <0.05). The total effective rate in the treatment group was 93.5%, higher than that in the control group (75.8%, P <0.05). The incidence of adverse reactions in the treatment group was 4.8%, which was 8.1% less than that in the control group (P <0.05). Conclusion Pulmicort respiration inhalation of pediatric bronchiolitis has a significant effect, can effectively improve the clinical symptoms of children, and simple operation, high safety, it is worth promoting the use of the clinic.