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目的 :观察整肠生与双嘧达莫联合治疗小儿轮状病毒肠炎的临床疗效。方法 :在一般治疗的基础上将 15 6例分别采用二药联合与单用双嘧达莫两种给药方案 ,比较两种不同给药方案的疗效差异。结果 :两种给药方案的显效率、总有效率、72hRV Ag转阴率、止泻时间均有明显差异 (P <0 .0 1)。结论 :小儿轮状病毒肠炎存在肠道微生态失衡 ,微生态制剂整肠生能调整这种失衡 ,并能促进肠绒毛上皮细胞的增生修复 ,联合抗病毒药物双嘧达莫具有明显的优越性 ,提高了临床疗效。
Objective: To observe the clinical efficacy of combined treatment of bowel disease and dipyridamole in children with rotavirus enteritis. Methods: On the basis of general treatment, 156 patients were treated with two drugs combined with dipyridamole alone two kinds of programs to compare the efficacy of two different regimens. Results: The apparent effective rate, total effective rate, 72hRV Ag conversion rate and antidiarrheal time of the two kinds of dosing regimens were significantly different (P <0.01). Conclusion: There is intestinal microecology imbalance in pediatric rotavirus enteritis. The probiotics of the whole intestine can adjust this imbalance and promote the proliferation and repair of intestinal villous epithelial cells. The combined anti-viral dipyridamole has obvious advantages , Improve the clinical efficacy.