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目的:探讨双水平气道正压通气治疗慢性阻塞性肺病Ⅱ型呼吸衰竭的临床疗效。方法:对35例慢性阻塞性肺病Ⅱ型呼吸衰竭的患者采用双水平气道正压通气进行治疗,分析无创正压通气(NIPPV)治疗前后动脉血pH值、动脉血氧分压(PaO2)、动脉血二氧化碳(PaCO2)、心率(HR)、呼吸频率(RR)等指标的变化。结果:实施NIPPV 3 h后即能改善患者的动脉血pH值、PaO2、PaCO2,减慢HR、RR;治疗72 h后与通气前比较差异有统计学意义(P均<0.01)。结论:使用NIPPV治疗慢性阻塞性肺病Ⅱ型呼吸衰竭疗效确切,且使用时间长效果更好。
Objective: To investigate the clinical effect of bi-level positive airway pressure ventilation in treating respiratory failure of type Ⅱ chronic obstructive pulmonary disease. Methods: 35 patients with COPD type Ⅱ respiratory failure were treated with bi-level positive airway pressure ventilation. The arterial blood pH value, PaO2, NEPV before and after non-invasive positive pressure ventilation (NIPPV) Arterial carbon dioxide (PaCO2), heart rate (HR), respiratory rate (RR) and other indicators of change. Results: Arterial blood pH, PaO2, PaCO2 and HR, RR were both improved after 3 hours of NIPPV treatment. There was significant difference between the two groups after 72 hours of treatment (P <0.01). Conclusion: The treatment of chronic obstructive pulmonary disease (COPD) type Ⅱ respiratory failure with NIPPV has definite curative effect and long-term effect.