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通过观测肝硬化患者经颈静脉肝内门体支架分流（ＴＩＰＳ）术中肝前、后血中的铁铜锌含量变化，旨在探讨肝脏对铁铜锌的调节作用。结果显示肝静脉血中的铁含量明显高于外周和门静脉血中的铁含量，提示在没有肠道吸收铁的情况下（空腹），肝脏动员自身贮藏的铁来满足人体的生理需要。推测，肝脏对铁的吸收、贮藏和代谢是一个主动的过程。门静脉血中的铜含量明显低于肝静脉和外周血中的铜含量，而肝静脉与外周血之间的铜含量差异无显著性意义。提示肝脏在维持机体铜代谢平衡方面起着决定性的作用。肝静脉、门静脉以及外周血中锌的含量差异无显著性意义。提示肝脏对锌未起明显的调节作用。
By observing the changes of iron, copper and zinc before and after operation in hepatic cirrhosis patients via transjugular intrahepatic portosystemic stent shunt (TIPS), the aim of the study was to investigate the regulation of iron, copper and zinc in the liver. The results showed that the content of iron in hepatic vein was significantly higher than that in peripheral and portal venous blood, suggesting that in the absence of intestinal absorption of iron (fasting), the liver mobilized its own stored iron to meet the physiological needs of the human body. Speculated that the liver’s absorption of iron, storage and metabolism is an active process. The content of copper in portal vein blood was significantly lower than that in hepatic vein and peripheral blood, but there was no significant difference in copper content between hepatic vein and peripheral blood. Suggesting that the liver plays a decisive role in maintaining the balance of copper metabolism in the body. There was no significant difference in the content of zinc in hepatic vein, portal vein and peripheral blood. Prompted the liver did not significantly regulate the role of zinc.