细胞黏附分子(cell adhesion molecule,CAM)是一类可在多种细胞上合成表达,存在于细胞膜或胞外,促进细胞与细胞、细胞与细胞外基质间黏附及相互作用的一类分子的总称。它们是一些糖蛋白,在炎症、肿瘤转移、免疫反应、伤口愈合等过程中发挥着重要作用。近年,CAM在新生儿疾病中的作用已引起人们研究的极大兴趣并取得了不少进展。现就目前这方面的研究进展综述如下。 Cell adhesion molecule (CAM) is a general term for a group of molecules that can be synthesized and expressed on many kinds of cells, exist in the cell membrane or extracellular, and promote the adhesion and interaction between cells and cells, cells and extracellular matrix. . They are glycoproteins that play an important role in inflammation, tumor metastasis, immune response and wound healing. In recent years, the role of CAM in neonatal diseases has drawn great interest and made considerable progress. Now on the current research progress in this area are summarized below.