目的:建立肝乐舒颗粒的质量标准。方法:采用TLC法对方中的灵芝、五味子进行定性鉴别;采用HPLC法对处方中的丹参酮ⅡA进行含量测定。结果:TLC斑点清晰、分离度好、专属性强,阴性对照无干扰;丹参酮ⅡA的进样量在0.2～4.0μg范围内与峰面积积分值呈良好线性关系,平均回收率98.34%,RSD=1.86%(n=5)。结论:所建标准能有效控制肝乐舒颗粒的质量。 Objective: To establish the quality standard of Ganshushu granule. Methods: TLC and TLC were used to identify the Ganoderma lucidum and Schisandrae chinensis respectively. The content of tanshinone ⅡA in the prescription was determined by HPLC. Results: The TLC spots were clear, the resolution was good, the specificity was strong, and the negative control had no interference. The injection volume of tanshinone Ⅱ A showed a good linear relationship with the peak area integral within the range of 0.2-4.0 μg, with an average recovery of 98.34% and RSD = 1.86% (n = 5). Conclusion: The established standard can effectively control the quality of Ganshushu granule.