目的　调查上海市近 10年来妊娠高血压综合征 (妊高征 )的发病情况及对母婴的影响。方法　对上海市区 8所医院 1989～ 1998年 10年间的妊高征发病情况进行回顾性分析。结果　15 8790例住院分娩孕产妇中 ,妊高征患者 885 2例 ,发生率为 5 5 7% ;其中轻度妊高征 4942例、中度妊高征 2 6 0 2例、重度妊高征为 130 8例 ;子痫 114例 ,占 1 2 9%。产妇死亡 1例 ,死因为DIC ;胎盘早剥 46例 ,占 0 5 2 % ;心功能衰竭 30例 ,占 0 34 % ;肾功能衰竭 18例 ,占 0 2 0 % ;DIC 6例 ,占 0 0 7% ;溶血、肝酶升高和低血小板计数 (HELLP)综合征 3例 ,占 0 0 3%。其中剖宫产 5 92 8例 ,剖宫产率 6 6 97%。围产儿 9197例 (双胎 34 3例 ,三胎 1例 ) ,围产儿死亡 6 6例 ,死亡率 7 18‰ ,其中死胎 48例 ,死产 12例 ,新生儿死亡 6例。结论　加强孕期保健宣教、母婴监护 ,开展妊高征的预防、早期诊断和治疗 ,有望降低妊高征发生率及围产儿死亡率 Objective To investigate the incidence of pregnancy-induced hypertension (PIH) in Shanghai in the past 10 years and the impact on mothers and infants. Methods The incidence of pregnancy-induced hypertension in 8 hospitals in Shanghai from 1989 to 1998 was retrospectively analyzed. Results 15 8790 cases of pregnant women in hospital delivery, pregnancy induced hypertension syndrome 8852 cases, the incidence was 57.7%; of which 4942 mild PIH, 266 cases of moderate PIH, severe PIH 1308 cases; eclampsia 114 cases, accounting for 119%. Maternal death in 1 case, the cause of death was DIC; 46 cases of placental abruption, accounting for 52.2%; 30 cases of heart failure, accounting for 0 34%; renal failure in 18 cases, accounting for 0 20%; DIC 6 cases, accounting for 0 0 7%; hemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome in 3 cases, accounting for 0 0 3%. Among them, 5 92 8 cases were cesarean section and 6 6 97% were cesarean section. There were 9,197 perinatal cases (343 twins and 1 tri-fetus). Six perinatal deaths occurred, with a mortality rate of 7 18 per thousand, of which 48 were stillbirths, 12 were stillborn, and 6 were neonatal deaths. Conclusion To strengthen the prenatal health education, maternal and child care, to carry out prevention and treatment of PIH, early diagnosis and treatment, is expected to reduce the incidence of pregnancy-induced hypertension and perinatal mortality