论文部分内容阅读
目的观察冠心病秽浊痰阻证患者血浆纤维蛋白肽A(FPA)及凝血酶激活纤溶抑制物(TAFI)水平与危险因素的关系。方法:选取2010年1月-2010年7月新疆维吾尔自治区中医医院住院患者中冠心病秽浊痰阻证患者88例于清晨抽取空腹静脉血,进行血浆纤维蛋白肽A(FPA)及凝血酶激活纤溶抑制物(TAFI)的检测并观察其与冠心病各危险因素的相关性。结果:冠心病秽浊痰阻证血浆纤维蛋白肽A:吸烟史、高脂血症、高血压等危险因素的偏回归系数在0.05的概率水平具有统计学意义;冠心病秽浊痰阻证凝血酶激活纤溶抑制物:高脂血症、高血压、糖尿病的偏回归系数在0.05的概率水平具有统计学意义。结论:高血压及高脂血症对冠心病秽浊痰阻证血浆纤维蛋白肽A及凝血酶激活纤溶抑制物水平均具有影响,吸烟对冠心病秽浊痰阻证血浆纤维蛋白肽A水平具有显著影响,糖尿病对冠心病秽浊痰阻证凝血酶激活纤溶抑制物含量具有影响,冠心病秽浊痰阻证患者合并上述危险因素时血液黏滞程度更高,血栓形成风险更大。
Objective To observe the relationship between plasma fibrinogen A (FPA) and thrombin-activated fibrinolysis inhibitor (TAFI) and risk factors in patients with turbid phlegm blocking syndrome. Methods: From January 2010 to July 2010, 88 cases of patients with coronoid phlegm and blood stasis syndrome in hospitalized patients of traditional Chinese medicine hospital of Xinjiang Uygur Autonomous Region were enrolled in this study. Fasting venous blood was collected in the early morning for plasma fibrinogen A (FPA) and thrombin activation Fibrinolysis inhibitor (TAFI) test and observe the risk factors associated with coronary heart disease. Results: The partial regression coefficients of plasma fibrinopeptide A: smoking history, hyperlipidemia, hypertension and other risk factors were statistically significant at a probability level of 0.05. Coronary heart disease, turbid phlegm blocking coagulation Enzyme-activated fibrinolysis inhibitors: hyperlipidemia, hypertension, diabetes partial regression coefficient at 0.05 probability level was statistically significant. CONCLUSION: Hypertension and hyperlipidemia have effects on serum fibrinolipid-A and thrombin-activated fibrinolysis inhibition in patients with coronary heart disease and turbid phlegm blocking. The levels of plasma fibrinolytic peptide A Has a significant effect, diabetes on turbinate phlegm blocking the thrombin-activated fibrinolysis inhibitor content, coronary heart disease turbid phlegm blocking the combination of the above risk factors, a higher degree of blood viscosity, thrombosis greater risk.