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[目的]观察急性冠脉综合征(ACS)患者PCI术后心率变异性(HRV)的变化,评估PCI对ACS预后的影响。[方法]选择我科2008年1月～2010年11月经PCI术治疗的ACS患者110例,观察术前、术后1周和术后3个月患者平均心率的变化,同时记录心率变异性的低频(LF)、高频(HF)及低高比值(LF/HF)的变化,并进行对比分析。[结果]与术前相比,PCI术后1周和术后3个月平均心率得到明显改善(P﹥0.05);与术前相比,HRV参数LF和HF显著升高,LF/HF显著下降,差异均有统计学意义(P﹤0.05)。[结论]PCI可以改善ACS患者的心率变异性,可能与PCI改善患者的心肌氧供氧耗平衡及纠正神经体液因子对心肌功能的调控失衡有关。
[Objective] To observe the changes of heart rate variability (HRV) after PCI in patients with acute coronary syndrome (ACS) and evaluate the effect of PCI on the prognosis of ACS. [Methods] A total of 110 patients with ACS treated by PCI from January 2008 to November 2010 in our department were enrolled. The changes of average heart rate before operation, 1 week after operation and 3 months after operation were observed, meanwhile heart rate variability The changes of LF, HF and LF / HF were compared and analyzed. [Results] Compared with the preoperative, the average heart rate of 1 week after PCI and 3 months after operation was significantly improved (P> 0.05). Compared with preoperative, the LF and HF of HRV parameters were significantly increased and LF / HF was significant Decreased, the differences were statistically significant (P <0.05). [Conclusion] PCI can improve the heart rate variability in patients with ACS, which may be related to the improvement of cardiac oxygen supply and consumption balance and the imbalance of cardiac myofascial regulation by PCI.