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目的报告一例异位在前列腺的嗜铬细胞瘤,探讨其发生机制及诊疗。方法回顾性分析我院收治的1例前列腺异位嗜铬细胞瘤患者的临床资料,总结归纳其临床特征及影像学表现,并结合文献进行分析。结果患者24h尿香草扁桃酸(VMA)等检查基本正常,CT及MRI检查示膀胱外侧,前列腺左侧叶凸出一大小约4.0cm×3.1cm×3.0cm肿块。予以行腹腔镜下前列腺肿瘤切除术,术后标本示肿物剖面呈金黄色,大小为4.0cm×2.8cm×2.0cm,有完整包膜,免疫组化结果:CgA(+),NSE(+),CD56(+),S100(-),Ki67(阳性率<1%),病理诊断为副节瘤。结论异位嗜铬细胞瘤较少见,异位在前列腺上嗜铬细胞瘤极为罕见,CT、磁共振成像(MRI)及~(131)I-间碘苄胍(~(131)I-MIBG)用于定位诊断,CT平扫+增强有其特异表现,腹腔镜手术可完整切除,确诊依据病理。
Objective To report a case of ectopic prostate in pheochromocytoma, to explore its mechanism and diagnosis and treatment. Methods The clinical data of one patient with ectopic pheochromocytoma treated in our hospital were retrospectively analyzed. The clinical features and imaging findings were summarized and analyzed in combination with the literature. Results The patients’ urine uremic acid and mandelic acid (VMA) and other tests were basically normal. The CT and MRI showed the outside of the bladder. The left lobe of the prostate protruded a size of about 4.0cm × 3.1cm × 3.0cm. Laparoscopic prostatectomy was performed. The postoperative specimens showed a golden yellow section with a size of 4.0cm × 2.8cm × 2.0cm. The complete envelopment was observed. Immunohistochemistry results showed that CgA (+), NSE (+ ), CD56 (+), S100 (-), Ki67 (positive rate <1%), pathological diagnosis of paraneoplastic. Conclusions Ectopic pheochromocytoma is rare and ectopic is extremely rare in the prostate. CT, MRI and 131I-131I-MIBG ) For positioning diagnosis, CT scan + enhanced its specific performance, laparoscopic surgery can be completely removed, the diagnosis based on pathology.