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目的:回顾性分析妊娠合并甲状腺功能减退的临床资料,研究其对妊娠结局及胎儿的影响。方法:选取2014年1月-2016年2月间在我院进行产前检查并生产的86例妊娠合并甲状腺功能减退的患者作为研究对象,根据其治疗后甲状腺功能的恢复情况分为控制组和控制不良组,控制组62例,控制不良组24例。在选择同期在我院产检并分娩的正常孕妇86例作为对照组,分析其临床资料,比较其不良妊娠结局的发生率。结果:控制不良组的不良妊娠结局高于控制组和对照组,三组比较具有统计学意义(P<0.05)。结论:妊娠合并甲状腺功能减退会增加不良妊娠结局的发生率,应该对孕妇开展甲状腺功能的早期筛查并给予有效干预。
Objective: To retrospectively analyze the clinical data of pregnancy complicated with hypothyroidism and study its effect on pregnancy outcome and fetus. Methods: From January 2014 to February 2016 in our hospital for prenatal care and production of 86 cases of pregnant women with hypothyroidism as the research object, according to the recovery of thyroid function after treatment is divided into control group and Control poor group, control group of 62 cases, poor control group of 24 cases. During the same period of selection in our hospital for quarantine and delivery of 86 normal pregnant women as a control group, analysis of clinical data, compared the incidence of adverse pregnancy outcomes. Results: The adverse pregnancy outcomes in poorly controlled group were higher than those in control group and control group, with statistical significance (P <0.05). Conclusion: Pregnancy complicated with hypothyroidism will increase the incidence of adverse pregnancy outcomes. Early screening of thyroid function should be carried out in pregnant women and effective intervention should be given.