β受体阻滞剂是治疗高血压病、心绞痛、心律失常、甲状腺机能亢进和焦虑状态等的常用药物,若同时服用其它药物则常发生药代动力学与药效动力学的相互作用,从而改变β受体阻滞剂或另一种药物的效应,增强或减弱药物的副作用,有时尚可造成死亡。因此,在临床上了解β受体阻滞剂的药物相互作用,合理应用β受体阻滞剂具有重要意义。以下就β受体阻滞剂与它药合用时的相互作用作一综述。 Beta blockers are commonly used drugs for the treatment of hypertension, angina pectoris, arrhythmia, hyperthyroidism and anxiety states, and pharmacokinetic and pharmacodynamic interactions often occur if other drugs are taken at the same time Changing the effect of a beta-blocker or another drug that increases or decreases drug side effects can sometimes cause death. Therefore, the clinical understanding of β-blocker drug interactions, the rational use of β-blockers have important significance. In the following, we will review the interaction between β-blockers and other drugs.