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应用放射性元素标记的化合物大大方便了药理学的研究。用化学合成法或生物合成法使C~(14)、S~(35)、I~(131)或P~(32)标记有机化合物,在过去的二、三年间起了很大的作用。特别是C~(14),因所有的有机化合物都含碳,且C~(14)的半衰期很长,所以C~(14)的应用最为广泛。但用C~(14)标记化合物有时很困难,也比较贵,加之C~(14)的半衰期很长,难以得到比活性很高的标记化合物,应用上受到一定的限制。随着液体闪烁计数技术的进展,已经可以很简单地测量H~3(即氚,或称T)的放射
The use of radiolabeled compounds has greatly facilitated pharmacological research. C 14, S 35, I 131 or P 32 labeled organic compounds by chemical synthesis or biosynthesis have played a significant role in the past two or three years. In particular, C ~ (14) is the most widely used C ~ (14) because all of the organic compounds contain carbon and the half life of C ~ (14) is very long. However, the labeling of compounds with C ~ (14) is sometimes difficult and expensive, and the long half-life of C ~ (14) makes it difficult to obtain labeled compounds with high specific activity. With the progress of liquid scintillation counting techniques, it has been very easy to measure the emission of H ~ 3 (ie tritium, or T)