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[目的]探索术前动脉化疗栓塞治疗对Ⅱb期宫颈癌的临床价值。[方法]52例Ⅱb期宫颈癌术前行髂内动脉或子宫动脉化疗栓塞,观察介入治疗的临床疗效。[结果]肿块消失8例(15.38%),肿块缩小超过50%者40例(76.92%),总有效率为92.32%。所有病人手术切缘均未见癌细胞,36例(69.23%)宫旁病灶大量坏死。术后平均随访18.4月,病人存活100%,无原位复发。[结论]介入化疗栓塞术简便、安全,是治疗Ⅱb期宫颈癌有效的术前辅助治疗手段,能有效控制局部肿瘤,减少淋巴转移,提高生存率。
[Objective] To explore the clinical value of preoperative arterial chemoembolization on stage Ⅱb cervical cancer. [Method] Fifty-two patients with stage Ⅱb cervical cancer underwent preoperative chemoembolization of internal iliac artery or uterine artery to observe the clinical effect of interventional therapy. [Results] The mass disappeared in 8 cases (15.38%), the mass reduced more than 50% in 40 cases (76.92%), the total effective rate was 92.32%. All patients had no cancer cells at the surgical margin, and 36 cases (69.23%) had a large number of paravertebral lesions necrosis. After an average follow-up 18.4 months, the patient survived 100%, no recurrence in situ. [Conclusion] Interventional chemotherapy and embolization is simple and safe and is an effective preoperative adjuvant therapy for stage Ⅱb cervical cancer. It can effectively control local tumors, reduce lymphatic metastasis and improve survival rate.