患儿,女,7岁,于1987年8月26日因智力严重低下,不会说话,生活不能自理就诊。系第1胎第1产、孕39周顺产。出生体重3100g、身长51cm、头围32.5cm,Apgar评分10,父母表型正常,非近亲婚配,患儿出生时父母年龄分别为25和22岁。体格检查身高115cm、体重16kg、头围48cm、坐高64cm、运动失调性步态。头型正常、眼距宽、牝 Children, female, 7 years old, on August 26, 1987 due to serious mental retardation, can not speak, life can not take care of themselves. Department of the first birth of the first fetus, 39 weeks of pregnancy, spontaneous. Birth weight 3100g, length 51cm, head circumference 32.5cm, Apgar score 10, the normal phenotype of parents, non-relatives marriage, the parents of children born at the age of 25 and 22 respectively. Physical examination height 115cm, weight 16kg, head circumference 48cm, sitting height 64cm, movement disorder gait. Normal head, wide eyes, 牝